Funny you should ask, I anguished over this questin for last three years. I read every book in my library, priced ammo til I was cross eyed, swapped guns right and left and swapped RH bolt for LH bolt and etc etc... went from 30.06 to 7mm RemMag to .270. In the past 40 yrs I've had 6 30.06 and 4 7mm RemMag and at least 6 .243 and I think FINALLY i have settled on the .270 with the new Hornady Superformance 130 SST or 140 SST for a do it all ( except grizzlers ) rifle. I have a LH Sav (with 3-9x40 Nikon dupplex) that I sorta like with the carbon stock but now am gonna switch to a LH Ruger 77 wood stock if I can find a older one. That otto last me til Im dead.

Good luck on your quest.