Another vote for the 243 Win. My daughter uses one. She's ionly 5' 4". I am not a fan of any smaller diameter bullets than 25 cal. class. Sure a deer can be cleanly killed with a 22-250 Rem. or 222 Rem. or 223 Rem. , etc. But why go there? The 243 Win. is superb, long proven, short action, mild recoil, good hunting ammo is easy to find .... that's be my choice. I'd stay with a 90-100 gr. medium game grade bullet. HAve to be careful not to be usuing a "varmint" buillet on deer. Now, if she can manage the recoil of a .410 shot gun, I'd go straight to a 7mm 08 Rem or 308 Win.