2 pellets and that Shockwave should work just fine if you put that bullet in the right place. Although IMO there are better bullets out there. I have read a lot of horror stories about the Shockwaves pushing a pencil hole through the deer and not expanding. One reason I would go to something like a Barnes or Nosler.
As for the scope, a 2-7x32mm will have you shooting out to those distance with ease. Also the close shots are easy if you turn the power down. I was shooting a Black Diamond XR at a paper plate out at 150 yards and the scope on that is a 1.5-4.5x32mm. Once I learned the drop it was easier then I thought to hit that plate.