Ok, I have a problem, I just bought a new set nice arrows and I am now hitting all over the place. First of all my setup is:

Hoyt AlphaMax
28in
65lb
New Arrows- Gold Tip Pro Hunter 5575 4in vanes
Wasp 100 grain 3blade braudheads
WB

With my old arrows I was using 3in quick spin speed hunter fletchings. And I think the old arrows were a bit lighter than my new arrows....... would the switch from 3in quick spin to 4in factory vanes cause a drastic change? Would it help if i re-fletched with helical vanes?

or

What steps should I take to re-tune my bow? Im lost on what to do.