6 years ago I shot a big spike through the heart, in fact the heart was nowhere to be found in the cavity, with a .30/06. That deer ran almost 250 yard before it piled up. It was a large clearcut in NH, and I watched him run. I thought to myself maybe I missed him. So I went to where he was standing when I shot him, and the blood trail was as wide as a city sidewalk, from impact point to where he dropped was all blood a blind man could have found him. He was running on pure adrenalin I would think.