When I went from 100 grains to 130 gr of 777 my poi at 100 yards was 8" higher. I wouldn't go over 130 gr if it was me. All my guns if loaded hotter than that begin to double or triple in group size. 100 to 130 gr is more than sufficient. I took 2 deer last year with a 100 gr and a 250 gr bullet. both dropped in less than 20 yards. one was a 223 yard shot and 1 at 234 yards. I would work up the load for accuracy. Accuracy is better than more powder in my book, especially with the right bullet