You are on a black powder site so I doubt you will get a lot of help; however I would personally not use a 180gr. bullet in a .308 for whitetail. The bullet is heavier than necessary and the extra recoil I would find uncomfortable. I don't like heavy recoil if not necessary. In fact for that reason when hunting whitetail my personal preference for a rifle is my 7X57 which is a tack driver and has very comfortable recoil. This rifle caliber has killed more elephant than any other caliber so I guess whitetail is a walk in the park.