If the primer will set one off without the powder and bullet in it then just load up like normal and shoot away... why waste the primers... it the firing pin will hit it, just shoot it.. you can use the de-priming pin in the die also, just don't slam it down, ease it down and you shouldn't have any problem whatsoever, if you don't feel safe, put some water in the case and deprime it that way !!
DSTATJUNK...in an ordinary hunting and plinking rifle, NO...they are so sloppy in the neck and chamber area that it doesn't matter.. in a benchrester with super tolerances, YES....but that's another story..