I have never had a problem with them. In my rifles they are accurate, easy to load, and very effective on game.
The trick is to load a heavy for caliber bullet, and keep the charges down. My last deer was with the 405 Gr. in front of 70 Gr. 2f Goex. Equal to the original 45-70 loading. Deer dropped like it was hit by lightning. I see no problem with them.