Originally Posted by spaniel

Not necessarily, it's just overkill and a waste of powder. You'll either blow the bullet outright or it'll fragment explosively because you impact with too much velocity.

I shoot 110gr V-Maxes in my 300WM for coyotes simply because I haven't put together a .243AI yet specifically for that purpose. THey shoot 3800fps, you could get them over 4000 out of your RUM. THey are accurate as all get-out.

The lighter bullets will also burn your barrel faster, which is why I don't shoot them much in my 300.