I've been to Colorado 2x's on archery hunts. Being from NY I'm around 800-1,000 ft tops. I didn't try any pills for altitude sickness, so I can't help you there. But I can give you a little advice on it if you decide not to take medications. First off the obvious is to be in the best shape you can. The better you can handle the elevations, the harder you'll be able to hunt. If you haven't been running, its time ya got going. My guide highly suggested running with a straw in my mouth to help. Regardless you will experience some altitude sickness, mostly in the form of headaches at least. I used Alieve for the headaches. It was the only thing that touched it, and what my outfitter suggested. If you have any stomach upset, rollaids work wonders. So pack some alieve, and rollaids. Also don't over eat your first couple days. Eat small portions, and no spicy foods. If your outfitter allows it, arrive a day in advance to just hang out, walk around. A adjustment day I call it. On your first day of hunt don't overdue it. Go easy to help in the adjustment. Of course the obvious, keep hydrated. You should be urinating clear, if not your not drinking enough. Thats about all I can tell ya on it. My first time the 2nd day I had some stomach upset, but I hate some spicy meatloaf the night before. The 2nd time all I dealt with was headaches, but I hate some rollaides before bedtime my first couple nights, just as precaution. Good Luck, its hunt of a lifetime!