RE: 40 S&W
I only use copper coated bullets with semis myself. I have had decent groups with 8.2gr of HS-6 with 155gr bullets. But surprisingly, I had awesome results with 7.7gr of Unique wtih 155gr bullets.
Everybody is used to Unique being very dirty when used with low recoil 44mag and 357mag loads. But I found when loaded to high pressures with smaller capacity cartridges like 9mm, 40S&W, and 357sig, it shot dead clean. Only drawback to loading unique is bad metering when compared to HS-6.