I have a similar CVA .45 - a Hunterbolt, not the Eclipse, but similar. Mine shoots the 225 grain Powerbelt very accurately with 70 grains of powder (2" groups at 100 yards). I don't use this load anymore, but I have no doubt that it would work very well for deer hunting. I'd seriously consider using either the 225 grain or 275 grainers instead of the 195. I know that the 195 can and has killed many deer, but it is a bit on the light side. If you want to use the 195, I'd limit my powder charge to 60-70 grains of powder and only take broadside, behind the shoulder shots.