ORIGINAL: HuntAway
I've used them in my Omega and got very good accuracy from them. My concern is a pure lead bullet pushed at 1800-1900 fps may just blow up on contact. I've switched to Nosler Partitions, every bit as expensive but are going to stick together no matter how hard you push them.The NP's are more accurate to boot!
I shot QTs for 2 years, took about 7-8 deer with the 250gr version. Worked fine, very accurate at about 1800fps. Switched to the .357 195gr Dead Center for another 2 years, took 8-9 deer. Again, very accurate and worked well at 100gr powder (2000 fps?).
Right now, no weight Dead Center is accurate in my Omega at a reasonable powder charge (90gr on up). HuntAway is correct, they are only good to about 1800 fps in most guns before accuracy deteriorates. However, within their accurate range they performed well on game for me.