ORIGINAL: Briman
I've heard of people using bullseye to help ignite big loads, not that I'd reccommend it with today's better powder technology.
I've heard of Elmer Keith experimenting with duplex loads a lot. He sacrificed a lot of handguns in his pursuit of knowledge though too.
It was quite common many years ago... even triplex loads were used. I don't know how many handguns, if any Keith blew up, but i do know that many who DID know what they were talking about, didn't thinkKeith was too bright. P.O. Ackley was one of them.