I've hunted antelope in MT and WY several times and have shot them with a .243, .270, and 7mm. The farthest was about 250 yards and the closest less than 50. If the topography is friendly where you're going, you may be able to wiggle in pretty close. Give it a try - if it doesn't work the first 10 times, number 11 might be the successful one. You'll probably be seeing lots of animals all day long and a few blown stalks may not matter. Regardless, it's super fun.