I think the 375 ruger will be the nail in the coffin for that bad boy. It is a vicious round though....I was watching the infamous Outdoor Channel( where all the hunts are ethical and nothing is shot within high fences). They were hunting brown bear and the guy that owns Crooked horn outfitters laid the boom on a nice brownie. The Bear looked like it was hit by a Terex going 80MPH ..Instantaneous kill...alll 4 legs stuck in the air Gave me a warm fuzzy inside