I don' t really see any advantage I just like both calibers

As a history buff for the .45LC and the .41mag because of a friend who thought it was the only caliber on the earth

He actually got me hooked.
I have never hunted big game with an auto but have doubt that a good 10mm will do the job for whitetail. I was comparing the cor-bon 185 grain loads the other day for the .357mag and the 10mm. The 10mm wins out on velocity and energy though not by much. Granted the .357mag is proably the least one should use according to many of the " experts"