RE: 22-250 range?
IF you are really going for accuracy, you need to handload for it, and develop the most accurate load you can. This will require testing a bunch of different bullets and powder types, maybe even cases and primers. BUT, only change ONE VARIABLE AT A TIME. Start with a good bullet of known accuracy, like aSierra 50 or 55-grain, and experiment with powders first.
With factory ammo, the most expensive may not shoot the best IN YOUR RIFLE!!! Even that "cheap $15.00/box remington" may prove to be the best. Again, as all rifles are individuals, you will have to test a lot of different loads to find the most accurate one. And when you do, you will need to buy a case ofit quick with the same lot #, as ammo can vary considerably from lot to lot, even in the "exact same load"!
I once had a .22/250 on a Mexican Mauser action. That rifle would keep all shots in the "V" ring of the Army "A" target at 500 yards on most days, unless the winds were over 10 MPH.