I've killed a couple of animals at 80+ yards. I would not try those shots today.Those were made back when the eyes were better and I felt bullet proof
I pretty much impose a 50 yard limit on myself now. It really depends on conditions. I passed a Super Buck this year at 8 yards because the shot would have been low percentage. There are times when a 45-50 yard shot is very high percentage shot. You just have to learn the difference. You for sure can Not shoot at every deer within 50 yards[8D]
Dan