MichaelH
This is strictly my opinion and other may have a different opinion. The .452/300 grain Gold Dot is probably more versitile. It will carry more energy and it will fly better over a greater distance (extended ranges).
The .452/250 on the other is my favorite for Whitetail. I personally believe i get quicker expansion at close ranges with this bullet vs the 300. This fact, I believe is very important when shooting a thin skinned Whitetail at close ranges. A couple of years ago I shot a realy nice 4x4 @ about 10 yards- the bullet went right through - made a very nice neat pencil hole through the animal. Same size whole in as out... He ran acouple hundred yards before pilingup - the worst part it was down hill. But that bullet was a300 grain Nosler Partition.
The gold dots will definitely stay together as they are bonded and have expansion control.
I am/was shooting a 100 grains of T7-2f and that is plenty - way plenty for Whitetail.
I am one of those lucky people that do not have the major "crud ring" problem with T7 - so I feel really confident in it.
What sabot are you normally shooting in the Wolf?