First in is set for 20 yds (level ground). If necessary, I hold 1" low at 10-15 yds from a tresstand but sometimes I just hold dead on and focus on maintaining form. Out to 25, I hold dead on. Things can happen quickly inside of 25 yards and one inch of difference in point of impact may take a back seat to making sure there are no limbs/bones/circumstances to prevent a clean shot.