...when both cartridges are handloaded, I believe the 444 Marlin has a pretty substantial edge on the 375... this thread caught my eye because I'm in the market for a Marlin in 375 right now. I think when handloaded to its full potential, it is an excellent medium bore... should be much better than the 30-30 class of cartridges. There's a good article by Paco Kelley about this cartridge at Sixgunner.com ........ I think that 500 dollars is somewhat high for even a NIB Winchester... I would think more along the lines of 425-450 tops.... Used ones are listed in Gun List for under 300....just not very many of them.... I missed a Marlin for 250...wasn't fast enough in my response. There is a used Winchester for 250 also...