There are a lot of considerations.Do you intend to go back to the same state and area repeatedly? If so DIY is the only way to go,especially if you are hunting deer.How much time will you have to devote to your trips,the longer the amount of time the more a DIY makes sense.
If you are hiunting larger species such as Elk or Moose do you have the equipment and knowledge to get the animal out of the woods in sufficient time not to ruin the meat? There are a lot more variables when hunting larger game and if taking a one time trip of this nature a good outfitter may make that trip a lot more pleasant.
It is definitely my preference to DIY,I like to have the outcome determined by my own efforts.
Contact Fish and Game in the states you wish to hunt ask to speak to the biologists for the particular species you wish to hunt,they can provide a lot of excellent information,tell them what your goals are and ask them given your goals what area's of the state should you be focusing on,sometimes they can even direct you to rental housing,cabin,house,motels etc.
If you decide to go the route of an Outfitter come back on the board here or PM me so myself and others here can help you with that process.There is nothing worse than a terrible outfitted hunt!