If your Ruger is like most, it shoots straight, and fast.

I' ve taken several coyotes with different .22lrs, and have had good success, that is, not one has ran away, I shoot them under the ear (where the skull is thinnest) or through the heart with a quartering away shot when I can enter the body through the " floating" ribs. I' d never shoot one over 50yrds away, and more often than not I double tap them just in case...which isn' t for everyone, I can bump fire my marlins, 10rnds in under 3 sec, or 17rnds in under 5, I can hit the same can three times before it falls off the fence. WHen Iknow I have a good shot, I don' t do that, but when they are good sized and I' m trying to go through the ribcage, it' s easier to let one bullet lead the other in.