The answer is which ever you rifle likes the best. Both are good bullets & preform well. FYI---I shoot plain jane 180 grain " Core-lokts" , " Power-Points" & Hornady " Spire-Points" out of my 30/06. Never had a problem with any elk, mulie, Mtn Goat, Bighorn sheep, black bear or antelope I taken here in Colorado over 25 years of using them. Plan on using the Hornady" Spire-Point" if I ever get drawn for a moose tag !