I'm going to try them in my gun this week. I checked their web sight and according to them you should zero at 2.17 inches high at 50 yards and they should be on at 100 yards. But thats just "their" balllistics data. Nothing substitues going out and putting in some range time. Every slug gun I own (3) I site in 2 inches high at 50 yards. Try that and I think you'll have better results. Two inches high at 50, on at 100 and 3-4 inches low at 125 shouldn't make much difference if you aim for the heart/lungs. Good luck.