I like the 2506 better then the 243. Recoil is comparable IMO. Another to consider is the 7mm 08, my wife will not touch my 270wins but she has absolutely no problems stepping behind the 7mm 08 I bought as a learning CF for thepotential newhunters in the fold. My 10 yo nephew had little trouble moving from my 22 250 to the 7mm 08 this summer - not a big kid either.

Good luck