Have you tried that rifle with full-bore conicals?
Funny you should ask,
Underclocked.
I'veshot one - and only one -target with Hornady 410 grain Great Plains over 120 grains Pyrodex and got an 8" five-shot group at 100 yards. The group had one bad flyer, with four of the shots into 3" (target below). My chronograph was out of commission at the time, so I don't know the velocity. It was a "stiff" load for sure.
The only other conicals I've shot were a few 250 grain REALs that average 2" at 50 yards. Never did a serious work up with them either.
Before I got my 25 ACP breech plug it seemed I would have a flyer in almost every five-shot group. That's not happening any more and I sure need to give conicals another try with a variety of loadings (so many possibilities - so little time). I got the Mustangafter last year's hunting season so I've haven't used it for hunting yet. All of my ML deer over the last 15 years have been killed with a TC New Englander and Great Plains 410s. It sure is a deadly bullet and deserves a better trial in the Mustang.