If you're willing to do some bareshaft testing, you can find the exact draw weight your arrows fly best at. This is where your draw weight should be set. This holds true for every setup. If you just crank it up without finding this out, and your arrows happen to fly weak, you may actually decrease penetration and the forgiveness of your arrows.

Assuming they have the proper spine, most bowhunters would be better off increasing tip weight, and decreasing draw weight.