My answer would depend on what kind of rifle & ignition system.
With an inline using 209 ignition about any powder on the market will light dependably. With a sidelock and #11 caps I'd stick with regular BP for hunting. Pyrodex would be my second choice. With any other powder I'd switch to musket caps or a 209 conversion nipple. (I have a few of Ben Hubbard's "mag-spark" conversion nipples and they work for lighting the new "replica"powders I've tried.)