No, a .45 ACP round in a half-moon clip will protrude from the cylinder too far to work in a revolver headspaced for the .45 COLT round-the .45 Colt case has a much thinner rim than results from the combined thickness of the .45 ACP and the clip. Take a look at the .45 Auto-Rim case, and compare that rim with the one on the .45 COLT round. You will see what I am referring to.

However, if you could get another .45 COLT cylinder from Taurus, the cylinder can be mounted in a lathe and the rear end of the cylinder can be turned off until the ACP round in the half-moon clip (or the .45 Auto-Rim case w/o clips) will headspacecorrectly in the frame. Doing thiswould be about the same operation as converting the British .455 Webley to use .45 ACP in clips (or the .45 Auto-Rim round w/o clips. MANY THOUSANDS of such conversions have been done since the end of WWII.)

Any decent revolver/pistol smith can do this simple conversion. Please let us know of your results! Get a copy of HANDGUNNER magazine-it's full of ads from such outfits.