It really depends on the distance. At slam dunk range out to say 25 yardsI aim at a line about a third up on the body. At longer ranges I aim for dead center. I figure that way it gives me more room for range estimation errors. That said, it depends on the deers attitude and state of nervousness. I have on occasion aimed at the belly line of super nervous deer and ended up with a dead center impact at less than 20 yards. It all comes with experience.