Mobo,
You are talking in front of the front leg and yes it can have the same effect as you can take out the same blood vessels (Aorta which is the main artery and I guess what is commonly called the juglar vein that is returning the blood back to the heart....the aorta is the one under lots of pressure as are all arteries)
The shot I'm talking about is that straight broadside shot that gets into that area just anterior of the heart (where you see the 3 blood vessels coming off like a fork) Many guys think incorrectly that the leg bone sits in this spot because it is centerline to slightly forward of centerline of the foreleg but its an open triangle to the quickest kill shot you'll see.

I don't advocate aiming there because it doesn't give you quite as much margin for error forward but like I said, if your POI drifts that direction and you hit that spot I don't think it's physically possible for that animal to get out of sight and the ones I've seen don't stop and lay down they go from sprint to crash in an instant. [:-]
On a broadside where you point of aim is straight up the crease of the back leg I would rather hit a few inches forward than a few inches back.
I think too many guys come up that crease and move their aim back slightly and bring the liver and guts into play too much........where in actuality you might be better served coming up the crease and favoring the centerline of the foreleg a touch more.

As you can clearly see by the 3D model if you stay just back of the crease on a broadside deer and keep your shot low you will be behind the heart entirely and flirting with the bottom of the lung lobes. These shots look awesome and your first instinct is "Heart Shot!" but it's not the same thing and you can see how much closer the guts are to the crease than the good stuff forward of it.

Me........I bring that pin justup from the "elbow joint" in the centerline of that foreleg into what is basically a heart hold. I don't like to come back off that crease at all.