Anything the .243 will do the .2506 will equal and/or better. IMHO it is a better cross over where deer are your primary target andespecially if theyare of a larger subspecies(stature). Noise difference can't it's enough for my eardrums to tell.

All this said if you'll be buying over the counter ammo you should do some checking locally to see whats available for your use. While the 2506rem is gaining followers the .243 is still more popular in this department. If reloading is in it's future - fo get bout it and enjoy the 2506.

As far as the T3 I really like it in the small/ some med cartridges. In fact had the LH T3 SS/2506remnot come with22.5" pipeI would have one primed and ready right now[&o]. Being a reloaderand what Iwant the rifle for I'd like to take advantage of the overbore nature of thecartridge with a longer barrel - 24" min but prefer it to be 26" in a perfect world. 22.5" barrels are common for production rifles and the likes of this cartridge...such is life