Yes, that is an excellent hunting load. If I could place my shot I would not even worry about shooting out to 125 yards with a load like that. Maybe even further if it was real accuate.

Too many people worry about velocity. Remember, the projectile is already almost 1/2 inch in diameter. Add to that some expansion on impact. That is more then some of the .30 caliber high velocity rifle bullets even expand, although like anything there are exceptions. While that 300 grain projectile will be moving at approxinatly 1521+/- fps (taken from Hodgon's manual for 300 gr XTP and 90 gr Pyrodex), there is a lot of energy there. The bullet should get excellent expansion and penetration.

I shoot conicals with 70 grains of powder, and they might be moving 1300+ fps. I have never worried about being under gunned when deer hunting.