My wife shot a huge buck 3 years ago. She was shooting the power belts,and 110gr. pyrodex. She shot the deer high in the sholder @ 25yds. to drop it right there. The impact knocked the buck down,but it got up and ran. We never found any blood,or the buck. She went back to her regular load of a 300gr. Hornady XTP,over 110grs. of pyrodex. She has dropped every deer she has shot with this load since.