The best powder i've found for the 110gr accubond and the 25.06 is RL22. I tried numerous powders beforethe RL22 which included imr4350, 4831, and7828 none of which shot very well. The imr4831 did show some promise with a couple loads but nothing that really stood out so i moved on to the RL22. I used the nosler 115gr load data pernosler tech support and started in the middle of the load range and worked up. I noticed right off the bat that the more powder i put in the case the better it shot. I hit the sweet spotat 53.5grs but shot a couple groups at 54grs and 54.5 to see if it would open up any. The 54gr load shot just as tight at 100yds but seem to open up more at 200yds and the 54.5 opened up about a 1/2" at 100yds so i ended up sticking with the 53.5. I've killed 6 deer with this load and all have fallen in the scope when i pulled the trigger. Here's the target of a 4shot groupusing53.5grs.
[On a side note, the imr4350 and 4831 both shot some impressive groups and accuracy with the Speer 120gr Spitzer.] Mike

Remington Classic 25.06
Rem Brass
Fed 210
RL22/53.5gr
COL=3.244 (0.010 off the lands in my rifle)