I have used the 180 grain Scirocco in my .300 Weatherby on deer and have been less than pleased. I specifically chose the Scirocco for this rifle because of its bonded core design. I felt it would perform better at the higher velocities than conventional bullets.

I have not lost a deer using this bullet, but I have experienced unneccessary meat damage because they expand too much in my opinion. My first experience was on a whitetail shot in the left ribs at a distance of about 25 yards. Muzzle velocity was about 3,150 fps, so it was still probably traveling over 3,000 fps on impact. I expected to find an exit wound, but instead, the bullet ended up under the hide over the right shoulder. Instead of making a straight wound channel through the ribs, it veered left, hitting the right shoulder and damaging meat I would have liked to have saved. This was because it had peeled all the way back to the base. There was virtually no bullet shank remaining and it was flat as a pancake. A bullet won't behave predictably if it doesn't retain a good portion of the shank.

In a high velocity application at close range I don't think these are the best bullets to use. They will kill, no doubt about it, but they don't behave predictably enough once inside the animal in my opinion. You may end up with more meat loss than what you want. I think they are better suited for milder velocities. However, if meat loss is no concern, then I would have to say these are as good as any other bullet out there for deer sized game.