I own both the 7mm-08 and the 280 Remington and love both of them. I hunted deer for years with a 7-08 Stainless A-Bolt and it's accuracy with factory loads was always excellent. I shot quite a few deer in several States and none ever took more than three steps. Then one day I walked into my local gun shop and picked up another A-Bolt Stainless (280 Remington) with a ported barrel and fell in love.
Of the two, the 280 allows me a bit more leeway in reloading heavier bullets. The 7-08, based on the .308 case limits you a bit but the 140gr class of bullets work incredibly well because bullet placement just seems easier with an inherently accurate cartridge.