Used to use heavy loads in my muzzleloaders myself. i never used anything under 130 grains of Pyrodex. Like to shoot muzzleloaders a lot. It screwed me up and got me into flinching so that my accuracy with cartridge rifles went all to heck.

Then something good happened to me. i have an old Staghorn with limits of 100 grains of Pyrodex. Shot a field dressed hog of over 350 pounds square through both shoulders with 100 grains of Pyrodex and a 250 grain SST bullet.That bullet went through16 to 19inches of bone, gristle and meat. Those heavy loads of powder are not needed for hogs or deer at 125 yards or less.Very long shots and shots at elk, moose and bear are another matter.

Heavy loads often cause those pistol bullets used in sabots to blow up and fail to penetrate game-if that is what you are after.Go to Hornady.com and look at the expansion specs for some of their XTP bullets.