It depends on your focus level. Some people find multiple pin sights distracting when a buck comes in and they have to find the right pin and pick a spot with rattled nerves, the more pins, the more chance of picking the wrong one. The disadvantage to a single pin is that if it's set for what you think is going to be a 20 yard shot and after you draw the animal presents a 30 yard shot, you've got to use some "Kentucky windage" or in this case; elevation. I'd generally say, the fewer pins the better but it's going to be a personal preference. Whichever you choose the most important thing is to learn your system well through practice, practice and more practice.