In capable hands the 204 ruger will & has been devastating on coyote, out to 300 plus yards. Like any cal. bullet placement is critical. Stay away from the front sholder bone & one may expect great results.

The 32 & 40 grain Hornady V-max bullets have been very effective, although the 35GR Berger has been most popular with coyote callers. Personally I am anxious to see how the new 45 gr. Hornady SP perform on the larger varmints.

The minimal recoil of this highly efficientchambering is the biggest selling point of this little round IMHO. The tiny .2” - .7” groupsat 100 yards don’t hurt either. I have a 223, 22-250 & 6mm also. And My CZ527 Varmint in 204 ruger is the rifle I would choose first when after coyote, especially if interested in keeping the pelts.