Be careful when mixing pellets, as if you are using 110 grs for pellets you are exceeding Hodgon's recommendations.

MAXIMUM LOAD WARNING
45 and 50 CALIBER RIFLE:
45 Caliber Pellets come in one size: 50 grain
50 Caliber Pellets come in two (2) sizes:
1) 50 grain volume equivalent which equals 50 grains of loose powder by volume.
2) 30 grain volume equivalent which equals 30 grains of loose powder by volume.
The maximum load per shot should never exceed total Pellets containing more than 100 grains volume equivalent. That means, no more than:





45 Caliber
1) Two (2) 50 grain Pellets


2) Three (3) 44/45 caliber 30 grain Pellets



50 Caliber
1) Three (3) 30 grain Pellets, or


2) Two (2) 50 grain Pellets, or


3) One (1) 50 grain Pellet and one (1) 30 grain Pellet


http://www.hodgdon.com/data/muzzleloading/pellet-warnings.php

100 grs is plenty of knockdown power out to 100 yards, if you need to shoot beyond that buy a centerfire rifle.