Do you mean real smokeless?! And 150gr at that!

Can you say "BOOOOOM!!!!!!!!"
as in you blow your face off!

Now if you are talking Black Powder substitute like Pyrodex, Triple Seven, etc. A reg rifle (not marked magnum) would be set for a MAX charge of 100gr, but maximun charges are not always best. Start with 80gr of black powder or one of it's substitutes and slowly work your way up to 100, 5gr increases at a time and see which one shoots best for your particular rifle and bullet.