I practice mainly to 35 but try to keep my actual hunting shots 25 and less. I practice some at 40 but not enough to shoot under hunting conditions. I'm sure if one practiced enough at longer distances it shouldn't be a problem. For myself, I know the distances in different directions around my stands and don't ever note anything past 25. Obviously the farther out the more chance of off target and knowing yardage becomes more critical. Me, I'd pass on that one. Dang it.