I think it really depends on other factors to keep them around. Any crops? How much of the hundred acres the house will take up? How much activity there will be around the house? Are there any exsisting farm land close by that the deer will move too?

I recently built a cabin on less than thirty acres that I own. It did not bother the deer at all. I actually had two bucks bedding close to the cabin when I went out there last week.

I would just recommend to not destorb them to much. There are also other deer managment techiniques to get them to stay around such as food plots.