Chasam60
I am currently using 100 grain t7-2f, but I am shooting 300 grain Noslers @ elk - actually those are .458's and I use a MMP .458 sabot.
For whitetail I was using Nosler260's, but I think I am switching to Speer .452 - 250 grain Gold Dots this season they have impressed me and are not as expensive - but I do shoot 110 grains t7-2f with these, but I am sure 100 grains would really be good....
They really shoot great for me. There are actually two types of 50/45 cal sabots out there. The older ones with a smooth cup are Harvester the newer ones with the stepped base are MMP's - the older harvesters load a little easier with .452 bullets - but the Noslers a .451 so they work well.
Good luck...