I would never try it but I was reading on another forum were some one shot a deer with a 22 long rifle behind the shoulders and it only went 40 yards and died. now if your talking 223, 22-250, 220swift they will kill deer fine at reasonable ranges but I would stray away from hunting with them in my state you cant use 22 calibers for deer

This subject gets alot of opinons and is about beat to death