RE: .243 for whitetail
My friends brother,(who gets ragged on alot for his 243), just killed an 200+ pound buck with one at 125 yards. The deer presented him with a head on shot for a few seconds, he waited until it turned broadside, and BINGO one dead rack buck. His brother(my friend) always tells him "you are going to lose one one day with that pea shooter", but he hasn't yet, and he has killed a number of hefty bucks with it